George Herman 'Babe' Ruth
William Bendix
Claire Hodgson Ruth
Claire Trevor
Colonel Jacob Ruppert
Matt Briggs
Dr. Menzies
Paul Cavanagh
Boston Braves' Rookie
Warren Douglas
Bill Carrigan, Red Sox Manager
Pat Flaherty
Mark Koenig
Boston Braves' coach
Richard Lane
Umpire Ziggy Sears
Ziggy Sears
Bucky Harris - Baseball Player
Bucky Harris
Harry Wismer - Sports Announcer
Harry Wismer
Mel Allen - New York Yankees Radio Announcer
Mel Allen
Brother Matthias
Charles Bickford
H. V. Kaltenborn - Radio News Commentator
H.V. Kaltenborn
Narrator
Knox Manning
Barfly (uncredited)
Al Bain
Reporter (uncredited)
Oliver Crawford
Phil Conrad
Sam Levene
Jack Dunn
William Frawley
Nightclub Singer
Gertrude Niesen
Miller Huggins
Fred Lightner
Western Union Boy
Stanley Clements
Babe Ruth as a Boy (as Bobby Ellis)
Robert Ellis
Gambler Dalton
Lloyd Gough
Director
Roy Del Ruth
Producer
Screenplay
George Callahan
Bob Considine
Makeup Artist
Mel Berns
Associate Producer
Joe Kaufmann
Set Decoration
Edward R. Robinson
Director of Photography
Philip Tannura
Editor
Richard V. Heermance
Original Music Composer
Edward Ward
Costume Design
Lorraine MacLean
Book
Art Direction
Frank Paul Sylos
Camera Operator
Wilbur Bradley
Grip
Harry Lewis