Questions arise when Senator Stoddard (James Stewart) attends the funeral of a local man named Tom Doniphon (John Wayne) in a small Western town. Flashing back, we learn Doniphon saved Stoddard, then a lawyer, when he was roughed up by a crew of outlaws terrorizing the town, led by Liberty Valance (Lee Marvin). As the territory's safety hung in the balance, Doniphon and Stoddard, two of the only people standing up to him, proved to be very important, but different, foes to Valance.
The simple story has the pair coming to the rescue of peace-loving Mormons when land-hungry Major Harriman sends his bullies to harass them into giving up their fertile valley. Trinity and Bambino manage to save the Mormons and send the bad guys packing with slapstick humor instead of excessive violence, saving the day.
A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.
The two brothers Trinity and Bambino are exchanged by two federal agents and take advantage of the situation to steal a huge booty hidden in a monastery by a gang of outlaws.
Jack Beauregard, an ageing gunman of the Old West, only wants to retire in peace and move to Europe. But a young gunfighter, known as "Nobody", who idolizes Beauregard, wants him to go out in a blaze of glory. So he arranges for Jack to face the 150-man gang known as The Wild Bunch and earn his place in history.
A coffin-dragging gunslinger and a prostitute become embroiled in a bitter feud between a merciless masked clan and a band of Mexican revolutionaries.
Don Jose disguises himself as Zorro, the masked freedom fighter, who tries to protect his people from the wrath of an evil military officer who is using his position to his own advantage.
Half-breed Keoma returns to his border hometown after service in the Civil War and finds it under the control of Caldwell, an ex-Confederate raider, and his vicious gang of thugs. To make matters worse, Keoma's three half-brothers have joined forces with Caldwell, and make it painfully clear that his return is an unwelcome one. Determined to break Caldwell and his brothers' grip on the town, Keoma partners with his father's former ranch hand to exact violent revenge.
The sole survivor of a bloody massacre vows revenge on his attackers and on the men who killed his wife.
An IRA operative escapes to the Americas and teams up with a circus singer to create a popular vaudeville act. When the singer falls for a rebel, they leave the circus behind to become fierce revolutionaries.
Crooked ranch foreman Thatcher sends his two henchmen, Parnell and Clint, out to murder his boss, wealthy Peter Arnold who has just arrived to retire on his ranch, bringing in tow his daughter, tomboy Jessie, who despises western life and can't wait to run off back to San Francisco. Stagecoach line owner Dave Collins and his sidekick Chito show up just in time to deter the attackers. Collins isn't done yet, though, as a gold shipment sent on one of his stages is stolen by Parnell and Clint, one of whom is recognized by Jessie, attempting to escape back to the west coast. Collins has his hands full trying to retrieve the stolen gold, and dealing with Jessie, who's fallen head-over-heels in love with him.
Hud Dixon returns to his hometown when his brother is killed by a lynch mob.
Steve McGowan has proposed to avenge the death of his father, murdered by one of the followers of Chief Miller. This engages the services of a famous gunslinger called Sabata and instructs him to kill Steve. The fate joins Steve and the Mexican bandit Leon Pompero, and together they decide to defeat the murderous gunman.
A thief takes the job as a town sheriff in order to rob a silver shipment before his ex-partner can grab it.
Lucky Luke becomes the Sheriff of Daisy Town and runs out all the criminals. Then the Dalton brothers arrive and try to get the Indians to break the peace treaty and attack the town.
The coming of the railroad to Cedar City spells the end of the stagecoach as the government gives the mail contract to the fastest means of delivery. McCord loses the stagecoach line gambling with the new buyer, but has enough hidden money to buy a ranch and some cattle. To make more money, he starts a gang to rob the railroad, express offices and steal cattle. But the railroads send out special agent Cameron to end his reign of violence.
Lucky's band of outlaws holds a rich girl for ransom and plans a new series of robberies. Meanwhile, a peasant who was widowed by one of Lucky's men teams up with a Preacher/Bounty Hunter to plot a premature end to Lucky's lucky streak.
After a bloody exchange with some bounty hunters, Anna, a veteran of the War in Afghanistan, and Gloria, her ill-prepared God-fearing friend, team up with a pair of coyotes to escape into Mexico.
Lash and Fuzzy sent to help John Watson with his stage line arrive to find him murdered. Recognizing the outlaws they trail them to their leader Baxter. But before Baxter can tell who the big boss is he is shot. After getting the stage through to assure the mail contract, Lash now realizes who the boss is.