Dorothy, and her big city lawyer boyfriend, return to the Lazy 'B' ranch to read her late father's will. For Dorothy to inherit everything, she must stay on the ranch for 5 years. If she does not, everything goes to Buck, who is the manager. She does not like Buck, so she makes a deal with the wrong people for cattle and then the outlaws go to the ranch to get the $10,000 from her. But Buck is on the job.
Tex rides to the rescue when badguys led by LaCrosse and Utah Joe kidnap Lettie.
A singing cowboy (Dick Foran) thwarts a thieving judge and courts a woman (Anne Nagel) in Texas.
Traveling with Doc Parker's medicine show, Gene finds his old friend Harry Brooks wounded and the Sheriff after him for murdering his father. Gene also sees that Craven and his gang are looking for Brooks. Finding clues that Craven was behind the murder, Gene has a plan utilizing the medicine show wagon that will trap the gang.
Poachers are harassing toll road owner Jen Larrabee. They want her land because it holds valuable minerals. Autry and the Cass County Boys, mistaken for Texas Rangers, help out.
Caxton has broken out of prison and Eddie has been sent to bring him in. Caxton is known by the polka dot band on his hat and Eddie has Soapy wear one like it. This gets Soapy arrested as soon as he rides into town but it leads Eddie to Varney and he realizes Varney will lead him to Caxton.
Deputies Gene Autry and Frog go up against modern cattle rustlers. These rustlers use technology such as, airplanes, radios and refrigerated trucks to steal the cows, butcher them in the field and ship them out before getting caught. This causes the town to bring in a modern NYC detective to catch the crooks, but will Autry and Frog be permanently out of a job?
Roy is a United States Marshal tracking down a counterfeiting ring and hunting down a mountain lion. Songs: "It's One Wonderful Day," "Rootin' Tootin' Cowboy," "Pancho's Rancho" and the title song.
Before he was murdered Grandpa Martin found a gold mine. He failed to record it and now everyone is looking for Martin's old horse that can lead them to it. When under-cover Texas Ranger Autry arrives to investigate, he is accused of the murder and finds the Sheriff after him.
A singing medicine-show cowboy and his magician partner catch a killer.
Gene returns from the East with new ranch owner Tom Bennett to find everyone's cattle dying. Blaine has reopened the copper mine and the waste is poisoning the water supply. While Gene is away Tom confronts the miners and a man is killed in the ensuing gunfight. Now Gene not only has the dying cattle problem but his ranch owner is in jail.
When asked about the Ghost Riders song he sings, Gene Autry tells this legend: Gene is about to resign as an investigator for the county attorney and go into the cattle business with his pal Chuckawalla Jones but decides instead to help Anne Lawson clear her father, rancher Ralph Lawson, of a false murder charge. He looks for the three witnesses who can testify that Lawson shot only in self defense in killing a gambler, but the witnesses are terrorized by another gambler, town boss Rock McCleary, who shoots witness Pop Roberts Morgan. Fatally wounded, Pop gives Gene the information needed to clear Lawson, then dies crying the "Ghost Riders" are coming for him. Gene then heads for a showdown with McCleary.
Gangster Chandler and his accomplice Tracy arrive at a dude ranch. Cowboy Kentucky arrives at the same time. When Tracy double-crosses his boss and has the stage robbed, Kentucky finds the outlaws and brings them in. Tracy frames him for the murder of the driver but his pal Cactus gets him out of jail. He returns just as Chandler shoots Tracy and Kentucky finds himself arrested for another murder.
Tex and his pals join the Rangers to fight rustlers along the border. When Doc and Pee Wee get framed for rustling and then jailed, Tex deserts the Rangers, crosses the border, and joins up with the outlaw gang hoping somehow to clear his pals.
A singing cowboy turns out to be a tenderfoot.
Three cowboys find that a U.S. Marshal relative is an impostor.
The drought-plagued ranchers of Sundown have to market their cattle at a loss in order to meet mortgage payments held by banker Cylus Cuttler. Then, Sheriff Tex Rockett is forced to quarantine all the cattle on the local ranches because of a hoof-and-mouth disease outbreak. Steve Davis herds his cattle to the railhead anyway, and Tex is forced to arrest him. Urged on by the banker's son, Nick Cuttler, the angry ranchers storm the jail, but Steve's sister Bee persuades them to await the trial. Steve, with Nick's help, breaks jail and is told he must kill Tex to aid the ranchers. Meanwhile, government man Bret Stockton and Tex see Nick and his men treating cattle in an unusual way. Tex finally proves that the Cuttlers have been treating the cattle with acid to give a false impression of the hoof-and-mouth disease.
A Hollywood scout averts disaster for a singing cowboy she has misled.
Marshal Landry captures outlaw Girard and bringing him in finds a woman and two children, the only survivors of an Indian attack. Later, transferring the prisoner his brothers free him. Then a stage is robbed of a silver shipment by Girard and his brothers. Examining telegrams gets Landry a confession from Girard's girlfriend. The telegraph line has been tapped and the telegrapher is the supposedly dead husband of the woman he brough in. Now knowing Girard's location he sets out after him.
Gene Autry becomes the new Sheriff after bank robbers kill the former sheriff. When Judge Beaumont is murdered, evidence points to the judge's wild son. Believing the young man, Gene tries to help.