James 'Jimmy' Isaac Neutron (voice)

Debi Derryberry

Judy Neutron / VOX (voice)

Megan Cavanagh

Nick Dean / Britney / PJ (voice)

Candi Milo

Yokian Guard / Gus (voice)

David L. Lander

Mr. Estevez (voice)

Carlos Alazraqui

Ultra Lord / Mission Control / General Bob (voice)

Jim Cummings

Bobby / Kid / Control Yokian (voice)

Keith Alcorn

Zachary / Reporter / Angie / Libby's Mom (voice)

Kimberly Brooks

Ms. Winfred Fowl (voice)

Andrea Martin

Bobby's Twin Brother (voice) / Butch (voice) / Jailbreak Cop (voice) / Old Man Johnson (voice) / Robobarber (voice) / Flurp Announcer (voice) / Yokian Officer (voice) / Anchor Boy (voice) / Guard (voice)

Billy West

Yokian Newscaster #2 (voice)

Mary Hart

Yokian Newscaster #1 (voice)

Bob Goen

Hugh Neutron / Pilot / Arena Guard (voice)

Mark DeCarlo

Norad Officer (voice)

Dee Bradley Baker

Hostess (voice)

Laraine Newman

Octapuke Kid / Guard / Bennie (voice)

John A. Davis

Guard (voice)

Paul Greenberg

Yokian Incubator Operator (voice)

Mark Menza

Little Girl / Camera Person (voice)

Jeannie Elias

Chris (voice)

Michael Hagiwara

Digital Voice (voice)

Richard Allen

Screamer (voice)

Brian Capshaw

Screamer (voice)

Cheryl Ray

Sheen Estevez (voice)

Jeffrey Garcia

Hyperactive Kid / Arena Yokian (voice)

Matthew Russell

King Goobot V (voice)

Patrick Stewart

Ooblar (voice)

Martin Short

Goddard / Poultra (voice)

Frank Welker

Carl Wheezer / Mr. and Mrs. Wheezer / Kid in Classroom (voice)

Rob Paulsen

Cindy Vortex (voice)

Carolyn Lawrence

Libby Folfax (voice)

Crystal Scales

Screenplay

John A. Davis

Producer

John A. Davis

Director

John A. Davis

Story

John A. Davis

Original Music Composer

John Debney

Concept Artist

Marc Gabbana

Producer

Steve Oedekerk

Screenplay

Steve Oedekerk

Story

Steve Oedekerk

Executive Producer

Julia Pistor

Producer

Albie Hecht

Executive Producer

Keith Alcorn

Editor

Gregory Perler

Screenplay

David N. Weiss

Editor

Jon Price

Director of Photography

Steve Kolbe

Director of Photography

Chris Sherrod

Screenplay

J. David Stem

Sound Designer

Michael Jonascu

Sound Re-Recording Mixer

David E. Fluhr

Sound Effects Editor

David Grimaldi

Sound Designer

Paul N.J. Ottosson

Supervising Sound Editor

Christopher T. Welch

Sound Re-Recording Mixer

Christian P. Minkler

Sound Effects Editor

Steve Tushar

Sound Effects Editor

Chuck Michael

Animation

Cheryl Ray

Animation

Matthew Russell

Producer

Keith Alcorn

Storyboard

Bob Camp

Animation

Brett Paton

Casting Director

Paula Kaplan

Art Direction

James Beihold

Unit Production Manager

Tok Braun

Production Manager

Kim Saxon

Production Design

Fred Cline

Casting Director

Ginny McSwain

Animation

Kirby Atkins

Animation

Jourdan Biziou

Animation

Brad Blevins

Animation

David L. Brehm

Animation

Brian Capshaw

Animation

Ray Chase

Animation

Ryan Davis

Animation

Andrea Davis

Animation

Ted Loo

Animation

Thomas Judd

Animation

Moses L. Hood

Animation

Tim Hatcher

Animation

Ben Williams

Animation

John Sore

Animation

Tim Pyle

Animation

Paul C. Allen