Eliza
Margarita Fischer
Uncle Tom
James B. Lowe
Loker
J. Gordon Russell
Aunt Chloe
Gertrude Howard
Mr. Shelby
Jack Mower
Mrs. Shelby
Vivien Oakland
Augustine St. Claire
John Roche
Aunt Ophelia
Aileen Manning
Mrs. St. Clare (uncredited)
Gertrude Astor
Captain (uncredited)
Francis Ford
Adolph (uncredited)
Rolfe Sedan
Sambo (uncredited)
Dick Sutherland
George Harris
Arthur Edmund Carewe
Phineas Fletcher (uncredited)
Nelson McDowell
Slave (uncredited)
Rondo Hatton
Johnson (uncredited)
C.E. Anderson
Auction Spectator (uncredited)
Carla Laemmle
Jeanette Loff
Slave at Wedding (uncredited)
Madame Sul-Te-Wan
Bidder at Eliza's Auction (uncredited)
Clarence Wilson
Simon Legree
George Siegmann
Cassy
Eulalie Jensen
Topsy
Mona Ray
Evangeline 'Eva' St. Clare
Virginia Grey
Little Harry
Lassie Lou Ahern
Lawyer Marks
Lucien Littlefield
Mr. Haley
Adolph Milar
Original Story
Harriet Beecher Stowe
Director
Harry A. Pollard
Executive Producer
Carl Laemmle
Director of Photography
Charles J. Stumar
Jacob Kull