Pee-wee Herman
Paul Reubens
Joe Manganiello
Emily
Katherine Vanderlinden
Beverly
Tara Buck
Pharmacist
John H. Mayer
Dan
Richard Riehle
Dudley
Dave Power
Sylvester
Josh Meyers
Clovis
Corey Martin Craig
Ernie
Paul Rust
Construction Worker
Robert R. Shafer
John Moody
Pepper
Jessica Pohly
Police Officer
Daniel Lue
Darrin Henson
Clayton Cannon
Gordon the Traveling Salesman
Patrick Egan
Panicked Female Passenger
Gloria Vassy
Panicked Male Passenger
Erick Chavarria
Clay
Frank Collison
Jimmy
Lynne Marie Stewart
Tourist at Snake Farm
Karen Maruyama
Farmer Brown
Hal Landon Jr.
Bella
Alia Shawkat
Linda Brown
Michelle Meredith
Louise Brown
Meredith O'Leary
Donna Brown
K.T. Wiegman
Diane Brown
Julie Ouellette
Janice Brown
Alexandra Ella
Betty Brown
Mary Karcz
Pam Brown
Lily Mae Harrington
Judy Brown
Mackenzie Marsh
Peggy Brown
Lindsay Hollister
Minister
Cooper Huckabee
Freckles
Stephanie Beatriz
Rene
Darryl Stephens
Brook
Dionne Gipson
Lane
Anthony Alabi
Wanda
Sonya Eddy
Penny King
Diane Salinger
Grizzly Bear Daniels
Brad William Henke
Abe
Leo Fitzpatrick
Ezekiel
Christopher Heyerdahl
New York City Policeman
Alan R. Rodriguez
Guy Who Bumps into Pee-wee
Michael Pauley
Yul / Party Coordinator (voice)
Jordan Black
Pizzeria Employee
Joseph Mancuso
DJ
David Arquette
Party Guest
Janina Gavankar
Kelly Bush Novak
Taymour Ghazi
Shelly
Nicole Sullivan
Abraham Lincoln
Robert Broski
Queen
Pamela Mant
TV Reporter
Thea Andrews
TV Cameraman
John Paragon
Mr. Murgatroyd
Doug Cox
Police Captain
Charles Robinson
Waitress
Maya Nalli
Man with Toupee (uncredited)
Deon Aumaier
Construction Worker (uncredited)
Ryan Nemeth
Mrs. Rose
Linda Porter
Ruby the Crossing Guard
Monica Horan
Marvin
Brian Palermo
ADR Voice Casting
Ranjani Brow
Original Music Composer
Mark Mothersbaugh
Foley Artist
Goro Koyama
Ashley Lambert
Supervising Sound Editor
George H. Anderson
Casting
Victoria Thomas
Stunt Driver
George Cottle
Makeup Department Head
Ve Neill
Writer
Co-Producer
Stunt Coordinator
Mark Rayner
Producer
Judd Apatow
Executive Producer
Richard Vane
Sound Re-Recording Mixer
Greg Orloff
Art Direction
Lindsey Moran
Dialogue Editor
Joe Schiff
Josh Church
Director
John Lee
Editor
Jeff Buchanan
Music Supervisor
Michael Turner
Director of Photography
Tim Orr
Production Design
Dan Butts
Set Decoration
Jennifer Lukehart
Script Supervisor
Diane Weiss
Tateum Kohut
Sandra Fox
Ted Sarandos
Larry Kemp
Costume Design
Karen Patch
Unit Production Manager
Rick Osako
Supervising Music Editor
Andrew Dorfman
Andy Malcolm
Costume Supervisor
Charlene Amateau
Steadicam Operator
Matthew A. Petrosky
Extras Casting
Chris Bustard
Transportation Coordinator
Russ Tolliver
Transportation Captain
Mike Miliotti
Sound Effects Editor
Luis Galdames
Sound Mixer
Agamemnon Andrianos
Hair Department Head
Kim Santantonio
"A" Camera Operator
Production Coordinator
Laura Altmann
Assistant Costume Designer
Kristen Kopp
Digital Intermediate Colorist
Siggy Ferstl
"B" Camera Operator
Kenneth Neil Moore
Still Photographer
Glen Wilson
Boom Operator
Brandon Loulias
Foley Mixer
Jack Heeren
ADR Mixer
Judah Getz
First Assistant Editor
Peggy Eghbalian
Casting Associate
Andrew Hadzopoulos
Property Master
Greg Finnin