William Thomas Green Morton
Joel McCrea
Elizabeth Morton
Betty Field
Betty Morton
Donivee Lee
Judge Shipman
Harry Hayden
Dr. Dahlmeyer
Torben Meyer
First Dental Patient
Victor Potel
Senator Borland
Thurston Hall
The Priest
J. Farrell MacDonald
Morton's Sign Painter - replaced by Hank Worden (uncredited)
Roscoe Ates
Onlooker (uncredited)
Hank Bell
Massachusetts Medical Society Man (uncredited)
Franklyn Farnum
Morton's Clinic Manager (uncredited)
Byron Foulger
Professor John C. Warren
Harry Carey
Morton's Sign Painter - replaced Roscoe Ates (uncredited)
Hank Worden
Presidential Secretary (uncredited)
Arthur Hoyt
Eben Frost
William Demarest
Dr. Horace Wells
Louis Jean Heydt
Dr. Charles T. Jackson
Julius Tannen
Vice-President of Medical Society
Edwin Maxwell
President Franklin Pierce
Porter Hall
Dr. Heywood
Franklin Pangborn
Homer Quimby
Grady Sutton
Makeup Artist
Wally Westmore
Original Music Composer
Victor Young
Costume Design
Edith Head
Screenplay
Preston Sturges
Director
Editor
Stuart Gilmore
Art Direction
Hans Dreier
Ernst Fegté
Writer
René Fülöp-Miller
Set Decoration
Stephen Seymour
Executive Producer
Buddy G. DeSylva
Director of Photography
Victor Milner