Dr. Slavkin O'Hara
Michael Sheen
Patricia Herman
Toni Collette
Young Billy Herman
Jamie Johnston
Tim Herman
Mark MacDonald
Tom Herman
Mickey MacDonald
Jimmy Herman
Cameron Kennedy
Alice O'Hara
Kate Hewlett
Delivery Room Doctor
Kevin Hare
Brian the Bully
Austin Macdonald
Miss Abda
Mishu Vellani
Malcom's Dad / Nurse Stewart
Aaron Abrams
Henry James Herman
Jason Spevack
Audrey O'Hara
Samantha Weinstein
Kindergarten Teacher
Melyssa Ade
Oprah
Oprah Winfrey
Stan Herman
Frank Moore
Dr. Gunther Flowers
Paul Braunstein
Young Patricia Herman
Hannah Brigden
Mother Herman
Sarah Orenstein
Producer
Sukee Chew
Executive Producer
Julia Roberts
Lisa Roberts Gillan
Director of Photography
Daniel Moder
Director
Dennis Lee
Philip Rose
Editor
Joan Sobel
Art Direction
Peter Grundy
Deepak Nayar
Production Design
Robert Pearson
Original Music Composer
David Torn
Casting
Tina Gerussi
Makeup Department Head
Geralyn Wraith
Sound Mixer
Jonathan Wales
Sound Editor
Chris Terhune
Simon Taufique
Sound Re-Recording Mixer
Jason Gaya
Stephanie Corsalini
Set Decoration
Jim Lambie
Hair Department Head
Lucy M. Orton
Daniel Norwick
Costume Design
Debra Hanson
Screenplay