Rosario, the niece of the rancher, returns to the ranch after ten years of absence. She takes in Margarito, a worker at the ranch, who is immediately smitten by her. Rosario is rescued from a runaway horse by the Seven Men, an outlaw a la Robin Hood that steals from the rich and gives to the poor. He also happens to be the twin brother of Margarito, unbeknownst to him. The confusion between Margarito and the Seven Men generates great comical situations in the film.
Questions arise when Senator Stoddard (James Stewart) attends the funeral of a local man named Tom Doniphon (John Wayne) in a small Western town. Flashing back, we learn Doniphon saved Stoddard, then a lawyer, when he was roughed up by a crew of outlaws terrorizing the town, led by Liberty Valance (Lee Marvin). As the territory's safety hung in the balance, Doniphon and Stoddard, two of the only people standing up to him, proved to be very important, but different, foes to Valance.
The simple story has the pair coming to the rescue of peace-loving Mormons when land-hungry Major Harriman sends his bullies to harass them into giving up their fertile valley. Trinity and Bambino manage to save the Mormons and send the bad guys packing with slapstick humor instead of excessive violence, saving the day.
Cole Thornton, a gunfighter for hire, joins forces with an old friend, Sheriff J.P. Harrah. Together with a fighter and a gambler, they help a rancher and his family fight a rival rancher that is trying to steal their water.
Hud Bannon is a ruthless young man who tarnishes everything and everyone he touches. Hud represents the perfect embodiment of alienated youth, out for kicks with no regard for the consequences. There is bitter conflict between the callous Hud and his stern and highly principled father, Homer. Hud's nephew Lon admires Hud's cheating ways, though he soon becomes too aware of Hud's reckless amorality to bear him anymore. In the world of the takers and the taken, Hud is a winner. He's a cheat, but, he explains, "I always say the law was meant to be interpreted in a lenient manner."
An ex-con seeks revenge on the man who put him in prison by planning a robbery of the latter's stagecoach, which is transporting gold. He enlists the help of a partner, who could be working for his nemesis.
Jim Craig has lived his first 18 years in the mountains of Australia on his father's farm. The death of his father forces him to go to the lowlands to earn enough money to get the farm back on its feet.
An aging Texas cattle man who has outlived his time swings into action when outlaws kidnap his grandson.
Ageing, wealthy, rancher and self-made man, George Washington McLintock is forced to deal with numerous personal and professional problems. Seemingly everyone wants a piece of his enormous farmstead, including high-ranking government men and nearby Native Americans. As McLintock tries to juggle his various adversaries, his wife—who left him two years previously—suddenly returns. But she isn't interested in George; she wants custody of their daughter.
When Rocklin arrives in a western town he finds that the rancher who hired him as a foreman has been murdered. He is out to solve the murder and thwart the scheming to take the ranch from its rightful owner.
Renegades trying to get the army to abandon their fort get the Indians addicted to whiskey, then convince them to attack and drive out the soldiers.
A woman seeking revenge for her murdered father hires a famous gunman, but he's very different from what she expects.
Banker Mason is after the ranchers land so he can resell it to the railroad for a profit. He has the railroad agent killed and replaces him with his stooge who then offers even less than Mason. But Rocky eventually suspects Mason and when Bill Anderson informs him the agent is a fake, they head out after Mason
Gunslinger Clayton Drumm is about to be hanged when he is given a chance to live if he agrees to murder Matthew, a miner who has steadfastly refused to sell his land to the railroad company. Matthew’s refusal is a major obstacle to the railroad’s plans for expansion.
Rancher Reynolds has fired his men and hired killers and is now using a crooked land deal to put the other ranchers off their land. Calico finds the reason why when he runs into his old nemesis Porter.
When Colt kills the men that murdered his father, he escapes his pursuers and joins Wolf and his outlaw gang. After two years Wolf breaks up the gang, deeds his ranch to Colt, and turns himself in. Now an honest rancher, things are going fine for Colt until Wolf's old gang shows up under a new leader. Colt get the Governor to release Wolf claiming the two of them can bring in the gang.
A cowhand named Bob Blake visits with Sally Thompson and her kid-brother, Jimmy, on their hard-scrabble homestead adjoining the Steele Ranch where Bob works. He learns that their father just died, and he plans on seeing if he can make things a bit easier for them.
An ex-con returns to his rural Ontario roots and outwits a corrupt and wealthy thoroughbred owner trying to take over a slew of local farms. Ray Dokes, a charming ex-ballplayer, returns from jail to discover the rural landscape of his childhood transformed by urban development. Determined to stay out of trouble, Ray heads to the farm of his old friend Pete Culpepper, a crusty Texas cowboy who trains losing racehorses and whose debts are growing faster than his corn.
Having quit their old gang and gone straight, Bert Allen and Joe Kemp finally own their own ranch after three years, but Joe robs the Riverton bank of the Green River Dam payroll - using Bert's horse, gun and gloves and leaving behind Bert's hat.
When attacked by two dogs, Joe Gilmore leaves them on the desert to die. Later one of the dogs saves John Blake from drowning. Men arrive claiming the dog is killing their chickens. They want to kill the dog but John convinces them the dog's fate should be determined by a trial.