In the year 80 AMM (After Mickey Mouse) on planet X the crime-syndicated Cats try to erase the Mouse-population once and for all. A scientist of the mice, prof. Fushimishi seems to have found the weapon against the threat - so Intermouse calls its best (albeit retired) agent, Nick Grabowsky, to get the plans. As a distraction for the Cats, they also send a second agent - Seargent Lazy Dick - for the mission.
Jerry and his diapered little mouse friend flood the kitchen, then use the freezer to turn it into a skating rink. Even though Tom finds a pair of ice skates, the mice have no problem outmaneuvering him.
Mickey Mouse, piloting a steamboat, delights his passenger, Minnie, by making musical instruments out of the menagerie on deck.
It's Christmas Day in the home of Granny, and her pet cat Sylvester delights at chasing her new Tweety Bird and takes fright at the bulldog unwrapped from under the tree.
Mickey Mouse and his friends must stop hundreds of old film reel versions of Mickey from wreaking havoc all over town.
Jerry removes a tack from Spike's paw. In gratitude, Spike gives Jerry a bell to ring when he's in trouble.
Professor Jerry teaches a course in how to outwit cats, but his pupil seems to know more than Jerry.
A baby elephant rolls off the circus train and right into Tom's bed. He quickly allies himself with Jerry, and with a rolled-up trunk and some paint, passes himself off as a giant mouse. The two then keep trading places to the bafflement of Tom.
Jerry Mouse befriends a newly hatched duckling who can't swim and ends up protecting him against his feline nemesis, Tom.
A baby seal escapes from the circus and ends up in Jerry's backyard pool. Tom finds out soon enough, and when the circus offers a $10,000 reward, his goal is clear.
At the home of Viennese composer Johann Strauss lived Johann Mouse. Whenever the composer played his waltzes, the mouse would dance to the music, unable to control himself. One day, when Strauss was away, the house cat played his master's music. When word got out about a piano-playing cat and a dancing mouse, they were commanded to perform for the emperor.
Bandit Pistol Pete enters a lawless western town and robs a bank. The town is in desperate need of a sheriff. Enter wandering cowboy Goofy who notices a pretty girl being held up in a stagecoach robbery by Pete. Lovestruck and completely oblivious to Pete, he foils the robbery while getting to know the girl better. This earns him a reputation as a great gunslinger and he is challenged to apprehend Pete. Pete tries to get his revenge on Goofy but every attempt backfires due to Goofy's clumsiness usually directed unintentionally at Pete.
Jerry's little duckling friend is depressed because he's just read The Ugly Duckling and thinks that he's ugly. Jerry does his best to help. Tom gets involved when the suicidal duck offers himself as a meal.
A moment after a bottle of white shoe polish pours on Jerry, Tom hears on the radio that a white mouse, having swallowed an explosive, has escaped from an experimental laboratory and that slightest jar of the mouse could cause it to explode and blow up the entire city. It is then that Tom notices now-white Jerry and concludes it's the escapee.
Tom and Jerry need to repeatedly come to the rescue when a teenage babysitter, supposed to be looking after the baby, is more interested in talking on the telephone than in paying attention to the baby who keeps crawling away.
Garfield and Odie fantasize that they are on a Middle-East mission to retrieve the Banana of Bombay, the symbol of humour to nations around the world.
After Tom's mistress orders him to clean up the mess he made while chasing Jerry, Tom spies an ad for a cat needed as companion to an old lady. Tom leaves his current home for what he anticipates will be a better life, only to discover the old lady is a witch.
Mickey is performing routine maintenance on his tugboat (with interference from a pelican) when a call comes on the radio that there's a sinking ship needing assistance. Sadly, Mickey's crew consists of Donald and Goofy, so getting underway to help is not easy. Goofy has to fight a boiler's door to get it stoked with coal (and when he succeeds, he overfills it) and Donald gets tangled up in the machinery. Not to mention that nobody casts off, so they drag half the dock along with them. The overworked boiler soon explodes.
A lost baby woodpecker, that believes Jerry is its mother, does everything it can to save the mouse from Tom, who is once again in pursuit. A CinemaScope remake of the 1949 Tom and Jerry cartoon Hatch Up Your Troubles.
A sequel to "A Cricket in Times Square," in this feature a musical cricket returns to his New York City home and his friends, a cat and a mouse, to discover the meaning of Christmas.