Questions arise when Senator Stoddard (James Stewart) attends the funeral of a local man named Tom Doniphon (John Wayne) in a small Western town. Flashing back, we learn Doniphon saved Stoddard, then a lawyer, when he was roughed up by a crew of outlaws terrorizing the town, led by Liberty Valance (Lee Marvin). As the territory's safety hung in the balance, Doniphon and Stoddard, two of the only people standing up to him, proved to be very important, but different, foes to Valance.
Retired wealthy sea captain Jim McKay arrives in the Old West, where he becomes embroiled in a feud between his future father-in-law, Major Terrill, and the rough and lawless Hannasseys over a valuable patch of land.
The simple story has the pair coming to the rescue of peace-loving Mormons when land-hungry Major Harriman sends his bullies to harass them into giving up their fertile valley. Trinity and Bambino manage to save the Mormons and send the bad guys packing with slapstick humor instead of excessive violence, saving the day.
A weary gunfighter attempts to settle down with a homestead family, but a smouldering settler and rancher conflict forces him to act.
In early 20th-century Montana, Col. William Ludlow lives on a ranch in the wilderness with his sons, Alfred, Tristan, and Samuel. Eventually, the unconventional but close-knit family are bound by loyalty, tested by war, and torn apart by love, as told over the course of several decades in this epic saga.
Cole Thornton, a gunfighter for hire, joins forces with an old friend, Sheriff J.P. Harrah. Together with a fighter and a gambler, they help a rancher and his family fight a rival rancher that is trying to steal their water.
A group of young gunmen, led by Billy the Kid, become deputies to avenge the murder of the rancher who became their benefactor. But when Billy takes their authority too far, they become the hunted.
Two friends hired to police a small town that is suffering under the rule of a rancher find their job complicated by the arrival of a young widow.
A woman seeking revenge for her murdered father hires a famous gunman, but he's very different from what she expects.
Renegades trying to get the army to abandon their fort get the Indians addicted to whiskey, then convince them to attack and drive out the soldiers.
After serving a five year prison sentence for allowing his men to destroy a town in a drunken spree, a trail boss is hired by the same town's leading citizen to drive their cattle to Fort Clemson. Complicating matters, a rival cattle baron also hires the cattle driver to lead his herd.
The Durango Kid is a sort of Robin Hood of the West who helps the lovely Walters (who replaced Starrett's usual love-interest, Iris Meredith), the daughter of a homesteader, defeat the evil MacDonald who has been terrorizing the decent citizens with his gang of rustlers.
Jim Killian arrives in a small Arizona town hoping to establish a peaceful life as the local preacher, but he soon finds himself in the middle of a feud between sheep ranchers and cattlemen. Leloopa, a young Native American woman, pleads for Killian's help after her shepherd father is hung by Coke Beck, the vicious son of the head cattle rancher. Killian must weigh his actions carefully lest he perpetuate the cycle of retribution and revenge.
Banker Mason is after the ranchers land so he can resell it to the railroad for a profit. He has the railroad agent killed and replaces him with his stooge who then offers even less than Mason. But Rocky eventually suspects Mason and when Bill Anderson informs him the agent is a fake, they head out after Mason
Marshall "Big Jim" Cole turns in his badge and heads to Wyoming with his family in order to settle on some land left him by a relative. He faces opposition both from a neighbor who wants that land for his own sons, and from a grizzly bear nicknamed "Satan" who keeps killing Cole's livestock.
Gene goes after the badguys after they kidnap the baby he should have been babysitting.
When Colt kills the men that murdered his father, he escapes his pursuers and joins Wolf and his outlaw gang. After two years Wolf breaks up the gang, deeds his ranch to Colt, and turns himself in. Now an honest rancher, things are going fine for Colt until Wolf's old gang shows up under a new leader. Colt get the Governor to release Wolf claiming the two of them can bring in the gang.
Two cowboys try to protect railroad workers from rampaging Indians.
An ex-con returns to his rural Ontario roots and outwits a corrupt and wealthy thoroughbred owner trying to take over a slew of local farms. Ray Dokes, a charming ex-ballplayer, returns from jail to discover the rural landscape of his childhood transformed by urban development. Determined to stay out of trouble, Ray heads to the farm of his old friend Pete Culpepper, a crusty Texas cowboy who trains losing racehorses and whose debts are growing faster than his corn.
When attacked by two dogs, Joe Gilmore leaves them on the desert to die. Later one of the dogs saves John Blake from drowning. Men arrive claiming the dog is killing their chickens. They want to kill the dog but John convinces them the dog's fate should be determined by a trial.