Tom enters from stage left in white tie and tails, sits at the piano, gets his focus as the orchestra in the pit beneath him warms up, and begins to play Liszt's "Hungarian Rhapsody". Unbeknownst to Tom and the audience, Jerry is asleep across several of the high-note keys inside the instrument, so Tom's playing eventually wakes him. Jerry is pummeled by hammers, bounced by wires, and squeezed by Tom as the cat tries to play the concerto while dispensing with Jerry. Jerry's defensive antics add to the brio of the program and answer Tom with Jerry's own skillful musical attack. By the concerto's end, the duet leaves only one animal standing for the audience's applause.

Jerry runs into a dog pound (and right on top of a napping Spike) to escape a rather mangy-looking Tom. To avoid being ripped to shreds, Tom borrows the head of a nearby dog statue. This easily fools the dogs, but not Jerry, and Tom keeps losing his newfound head...

Spike the bulldog, grateful to Jerry for getting him out of the dogcatcher's van, offers to help the little mouse any time he whistles. Tom, Jerry's feline tormentor, seeks to overcome this new disadvantage.

Spike is guarding a private fishing hole - in his sleep. Tom sneaks in to do some fishing - with Jerry as bait. But one particularly vicious fish turns out to be more than Tom or Jerry bargained for, particularly when he wakes up Spike.

Tom ties up Spike and sneaks into the courtyard of the glamorous Toodles Galore with his bass, hoping to woo her with his song, much to the annoyance of a sleeping Jerry.

When a bulldog threatens Tom to keep away from his puppy, Jerry realizes that sticking close to the boy is the best way to keep away his feline tormentor. But Tom is not about to let the mouse evade him so easily.

Chased by Tom around the barnyard, Jerry takes refuge under a hen, who, in her nest, is sitting on eggs. Tom has to figure out ways to get Jerry out from under the protective hen.

After being evicted from their old house by Tom's owner for causing major damage, cat and mouse Tom and Jerry enter a race entitled the "Fabulous Super Race" to win a mansion.

Jasper is given an ultimatum by his master: break one more thing and you're out. Rodent Jerry does his best to make sure that his tormentor "gets the boot".

The Bide A Wee Mouse Home has sent the orphan mouse Nibbles to spend Thanksgiving with Jerry. Unfortunately, Nibbles is always hungry.

Jerry Mouse befriends a newly hatched duckling who can't swim and ends up protecting him against his feline nemesis, Tom.

Tom steals an egg from a mother duck's nest, but soon the resultant hatchling runs away from the cat and into a mouse hole, where it finds an able protector in Jerry.

A baby elephant rolls off the circus train and right into Tom's bed. He quickly allies himself with Jerry, and with a rolled-up trunk and some paint, passes himself off as a giant mouse. The two then keep trading places to the bafflement of Tom.

A baby woodpecker mistakes Jerry for his mother. The mouse rejects the newly hatched bird but soon finds himself protecting it against his feline nemesis, Tom.

Tom is given the task of guarding the fridge during the night by Mammy-Two-Shoes, but as soon as he has started he is tricked by Jerry into falling into the basement, where he lands in a barrel of cider. Now drunk, Tom staggers around in the house getting up to no good with Jerry.

Tom is playing with Jerry when a cute lady cat is delivered to Mammy for her to take care of. Tom is smitten at first sight.

A baby seal escapes from the circus and ends up in Jerry's backyard pool. Tom finds out soon enough, and when the circus offers a $10,000 reward, his goal is clear.

Mammy Two-Shoes replaces Tom with a younger cat who is a lightning-quick mouser. Tom and Jerry form an alliance in order to get rid of this dangerous newcomer.

Mail call. Nothing for Tom, but at Jerry's box, Tom finds a package; inside is a book, "Life with Tom" by Jerry Mouse. As Tom flips to chapters and hears, first a radio audience, then a group of alley cats, then Spike and Tyke, all laughing over the book, we see the clips from earlier shows that everyone is laughing at. Tom gets more and more irate about being the butt of everyone's jokes, and confronts Jerry, clobbering him with the book, when Jerry shows Tom the rest of his mail. The royalty checks have come in, and Jerry has split his $50,000 royalty with Tom. Suddenly, with $25,000 in his pocket, Tom is able to find the book funny.

The kiddie radio host, Uncle Dudley, reminds his listeners that it is "Be Kind to Animals" week. Tom resolves to be kind to his mouse-nemesis, Jerry, but the cat changes his mind after sneaking a look at Jerry's diary.