Double-crossed and left without water in the desert, Cable Hogue is saved when he finds a spring. It is in just the right spot for a much needed rest stop on the local stagecoach line, and Hogue uses this to his advantage. He builds a house and makes money off the stagecoach passengers. Hildy, a prostitute from the nearest town, moves in with him. Hogue has everything going his way until the advent of the automobile ends the era of the stagecoach.
A scruffy garbage boy becomes the pupil of famed gunfighter Talby, and the stage for confrontation is set when the gunman overruns the boy's town through violence and corruption.
An independent former ranch foreman and an heiress are kidnapped by a trio of ruthless outlaws.
Joseph "Doc" Frail is a doctor with a past he's trying to outrun. While in Montana, he comes across a mining camp with a hanging tree and rescues a man named Rune from the noose. With Rune as his servant, Frail decides to settle down, and he takes over as town doctor. He meets Elizabeth, who is suffering from shock, and the two soon fall in love. But when Elizabeth is attacked, Frail's attempt to help her lands them both in trouble.
At a desolate relay station in the west, a stagecoach attendant and a stranded woman traveller are held captive by a band of escaped convicts.
It's 1876 and all the Indians are at peace except the Comanches lead by Black Cloud. When Black Cloud wipes out a town, only six soldiers are left and they head for the nearest fort. In the desert they are reinforced by members of a stagecoach and find some water at a deserted mission. Pinned down by Black Cloud they send an Indian boy who was Black Cloud's prisoner on to the fort while they try to bargain with Black Cloud whom they learn is without water.
In 1865, a troop of Confederate soldiers led by Major Matt Stewart attack the wagon of gold escorted by Union cavalry and the soldiers are killed. The only wounded survivor tells that the war ended one month ago, and the group decides to take the gold and meet their liaison that knew that the war ended but did not inform the troop. The harsh Rolph Bainter kills the greedy man and the soldiers flee in his wagon driven by Major Stewart. When they meet a posse chasing them, Stewart gives wrong information to misguide the group; however, they have an accident with the wagon and lose the horses. They decide to stop a stagecoach and force the driver to transport them, but the posse returns and they are trapped in the station with the passenger. They realize that the men are not deputies and have no intention to bring them to justice but take the stolen gold.
Jesse W. Haywood (Don Knotts) graduates from dental school in Philadelphia in 1870 and goes west to become a frontier dentist. Penelope "Bad Penny" Cushing (Barbara Rhoades) is offered a pardon if she will track down a ring of gun smugglers. She tricks Haywood into a sham marriage as a disguise. Haywood inadvertently becomes the legendary "Doc the Haywood" after he guns down "Arnold the Kid".
After a stagecoach holdup, Frank Slayton's notorious gang leave Ben Warren for dead and head off with his fiancée. Warren follows, and although none of the townspeople he comes across are prepared to help, he recruits two others who have sworn revenge on the ruthless Slayton.
A gunfighter, stranded in the desert, comes across the aftermath of a stage robbery, in which all the passengers were killed. He takes one of the horses to ride to town to report the massacre, but finds himself accused of it. He also finds himself accused of the murder of the local banker, and winds up hiding in the basement of a house where the local sheriff, who is very sick, lives with his daughter.
Author Robert Louis Stevenson takes a trip to Napa Valley, California, in 1880 and gets involved in the exploits of a stagecoach driver who captures a hooded highwayman called The Monk. Supposedly inspired by a true incident, this offbeat Western based on Stevenson's The Silverado Squatters is a dandy, high-spirited adventure yarn.
An evil gang is involved in both cattle rustling and the robbing of stagecoaches. Hoppy must stop them without help from the sheriff who turns out be a major outlaw himself.
The Pony Express is finished as the Post Office plans to award the mail contract to a stage line. Bill and his father put in a bid for the mail, however there are three bids close together. The officials will run a race to pick the winner, and the Banton Brothers sabotage Bill's stage. Mary still believes in Bill until they try to get rid of him by holding up the regular stage with his well-known horse. Bill needs proof to clear himself and expose the bad guys.
A bandit disguises himself as an officer in an attempt to woo a saloon singer.
Hoppy is busy chasing stagecoach bandits who sing as they rob.
Stagecoach robbers take the money Hoppy was going to use to buy cattle so Hoppy, California and Lin go after them.
In the late 19th Century, Mary Breydon, a widow, and Peggy Breydon, her daughter manage a stagecoach stop on The Cherokee Trail. The story is told from the perspective of Peggy, looking back on her adventures.
Jim Bannon and his partner own a stagecoach line. With the coming of the telegraph and the end of the Pony Express, two men plot to take over and get the new mail contract. When Jim's partner is murdered and Jim's name is written in the sand beside the body, Jim is arrested. At his trial Whip brings surprising evidence that clears Jim and the two plotters are soon arrested.
Caldwell and Nixon have their men rob the stage and then critcize the Sheriff for not catching the robbers. With her father the Sheriff under pressure, Mary sends for Hoppy who finds the stolen money and sets a trap to bring in the entire gang.
In order to obtain a stage coach mail contract, a new road must be built. A gang of outlaws try to prevent the building of the road.