Dr. Watson, who served in the English armed forces and was in the Afghan war, retires and returns to his homeland, in England. Since the financial situation of the doctor is very precarious, his long-time friend Mr. Stamford offers him to rent a room in the house at 221-B Baker Street, which is rented by an elderly lady - Mrs. Hudson. The second rented room is already occupied by another gentleman - the mysterious Mr. Sherlock Holmes. Holmes makes an ambiguous impression on Watson. He conducts complex chemical experiments with blood, plays the violin, has the deepest knowledge about cigar ash, London dirt and criminal law, but at the same time demonstrates complete ignorance of well-known truths (for example, the fact that the Earth revolves around the Sun), does not read fiction, as well as books on history and philosophy. At the same time, very strange visitors constantly come to Holmes, and on the table he has portraits of personalities of a disgusting appearance.

On his uncle's death Sir Henry Baskerville returns from Canada to take charge of his ancestral hall on the desolate moors of Devonshire, and finds that Sherlock Holmes is there to investigate the local belief that his uncle was killed by a monster hound that has roamed the moors since 1650, and is likely to strike again at Sir Henry.

There is a new criminal mastermind at large (Professor Moriarty) and not only is he Holmes’ intellectual equal, but his capacity for evil and lack of conscience may give him an advantage over the detective.

After the death of his wife, wealthy retiree Justin Playfair creates a fantasy world for himself in which he is the legendary detective Sherlock Holmes, even dressing like the character. Out of concern for Justin's money more than his health, his brother Blevins puts him under the care of psychiatrist Dr. Mildred Watson. As Dr. Watson grows fond of Justin, she begins to play along with his theories, eventually becoming an assistant in his investigations.

In World War II, a British secret agent carrying a vitally important document is kidnapped en route to Washington. The British government calls on Sherlock Holmes to recover it.

After the King of Ruthenia has been assassinated, Holmes and Watson are engaged to escort his son to Europe via Algiers, aboard a transatlantic ocean liner which also carries a number of suspicious persons, any of whom may be involved in a plot to also assassinate him.

England, at the start of World War Two. Mysterious wireless broadcasts, apparently from Nazi Germany are heard over the BBC. They warn of acts of terror in England, just before they take place. Baffled, the Defense Committee call in Sherlock Holmes.

Tom and Jerry need to learn to work together in order to help Sherlock Holmes with an investigation of a jewel theft. But still, they are cat and mouse!

Sherlock Holmes investigates when young women around London turn up murdered, each with a finger severed. Scotland Yard suspects a madman, but Holmes believes the killings to be part of a diabolical plot.

When Watson reads from the newspaper there have been two similar murders near Whitechapel in a few days, Sherlock Holmes' sharp deductive is immediately stimulated to start its merciless method of elimination after observation of every apparently meaningless detail. He guesses right the victims must be street whores, and doesn't need long to work his way trough a pawn shop, an aristocratic family's stately home, a hospital and of course the potential suspects and (even unknowing) witnesses who are the cast of the gradually unraveled story of the murderer and his motive.

After spending decades living in the shadow of his more famous and successful sibling, Consulting Detective Sigerson Holmes (Wilder) is called upon to help solve a crucial case that leads him on a hilarious trail of false identities, stolen documents, secret codes... and exposed backsides.

In London, a secret society led by lawyer Thaddeus Merrydew collects the assets of any of its deceased members and divides them among the remaining members. Society members start dropping like flies. Sherlock Holmes is approached by member James Murphy's widow, who is miffed at being left penniless by her husband. When Captain Pyke is shot, Holmes keys in on his mysterious Chinese widow as well as the shady Merrydew. Other members keep dying: Malcom Dearing first, then Mr. Baker. There is also an attempt on the life of young Eileen Forrester, who became a reluctant society member upon the death of her father. Holmes' uncanny observations and insights are put to the test.

Holmes takes a vacation and visits his old friend Sir Henry Baskerville. His vacation ends when he suddenly finds himself in the middle of a double-murder mystery. Now he's got to find Professor Moriarty and the horse Silver Blaze before the great cup final horse race.

Sherlock Holmes is a master at solving the most impenetrable mysteries, but he has his work cut out for him on his latest case. As the famed detective investigates an alleged theft, he’s brought face to face with his most devious adversary yet — Professor Moriarty.

A young woman turns to Holmes for protection when she's menaced by an escaped killer seeking missing treasure. However, when the woman is kidnapped, Holmes and Watson must penetrate the city's criminal underworld to find her.

Detective Sherlock Holmes and Dr. John Watson join forces to investigate a mysterious murder at Buckingham Palace. It seems like an open-and-shut case as all signs point to Professor James Moriarty, the criminal mastermind and longtime nemesis of the crime-solving duo. When new twists and clues begin to emerge, the world's greatest sleuth and his trusted assistant must now use their legendary wits and ingenious methods to catch the killer as they only have four days before the queen becomes the next victim.

The sensational details of a gruesome murder in The Daily Gazette have London in a panic, as a blood-thirsty madman - more vicious than Jack the Ripper - preys upon the city. Of greater concern to Scotland Yard, however, is that the account of the murder was published nearly two hours prior to the crime having been committed! Sherlock Holmes and Dr. Watson - the Great Detective and his faithful assistant and chronicler - find themselves challenged with one of their most baffling cases - "The Case of the Woman Who Was Murdered Tomorrow"! Will an innocent man be sent to the gallows? How much blood will be shed before a scarred fiend is brought to justice? ...And who are the mysterious Shadow Watchers, a coven of ominous figures who orchestrate terror from within the darkness? Starring Anthony D.P. Mann as Holmes and Terry Wade as Dr. Watson, "Sherlock Holmes and the Shadow Watchers" is a horrifying new adventure, produced with the kind permission of the Conan Doyle Estate*.

Sherlock Holmes is forced to confront his age and health condition as he struggles to solve the murder of a fellow detective.

A wealthy banker comes to Holmes desperate to recover a valuable British gem--and to deal with his son's apparent dishonor.

When Dr. Watson tries to apply Sherlock Holmes' method, he quickly discovers that it is harder than it looks.