Medic, in exchange for her life, healed Shinnosuke. Now, he and Heart use the last of their strength to destroy Sigma. After Sigma is destroyed, Heart challenges Shinnosuke for the last time to put an end their rivalry. However, Shinnosuke tries to call off the duel by convincing him to co-exist with humanity.

One year ago, Shinnosuke and Hayase were investigating the anti-government organization called Neo Shade. Now they’ve become active again, a Neo Shade thief breaks into the Metro Police Department to steal an item that had been left behind at a crime scene. The mysterious item, called a Ghost Eyecon, that had been left behind at the crime scene seems to be connected to the case.

Kazuhiko Takano is an agent for spy organizatoin "AN Tsuushin." His rookie partner is Ryoichi Taoka and they sneak into the International City Fair, which will be held in three years in Tokyo. Various schemes exists surrounding the selection of the construction site for the International City Fair. An explosion suddenly takes place in front of Kazuhiko Takano.