Rusty Griswold
Ed Helms
Debbie Griswold
Christina Applegate
Ethan
Ron Livingston
Trucker
Norman Reedus
Jack Peterson
Keegan-Michael Key
Nancy Peterson
Regina Hall
Sheila Peterson
Emyri Crutchfield
Gary Peterson
Alkoya Brunson
Colorado Cop
Nick Kroll
Utah Cop
Tim Heidecker
Arizona Cop
Kaitlin Olson
New Mexico Cop
Michael Peña
James Griswold
Skyler Gisondo
Ferrari Girl
Hannah Jeter
Harry Co-Pilot
David Clennon
Jake
Colin Hanks
Mom on Plane
Kirstin Ford
Boy on Plane
Ethan Maher
Heather
Elizabeth Gillies
Brooke
Cristina Squyres
Chelsea
Nadine Avola
Terry
Ryan Cartwright
Shuttle Driver
Valerie Payton
Kevin Griswold
Steele Stebbins
Husky Lady at Monument
O'Clair Alexander
Man on the Monument
Miles Doleac
Women at Monument
Holly Gardner
Furious Husband
R.F. Daley
Furious Wife
Elizabeth Fendrick
Male Guest
Michael H. Cole
Female Guest
Brooke Jaye Taylor
Male Guest #2
Matthew Cornwell
Wally World Kid #2
Mitchell Warren
Ride Operator
John Francis Daley
Stone Crandall
Chris Hemsworth
Gas Station Clerk (uncredited)
Brandon Michael Hale
Boobs (uncredited)
Libby Blake
Hawaiian (uncredited)
Rick Ericson
Reporter (uncredited)
Omar Lagudali
Young James (age 7 / 9) (uncredited)
Cameron McIntyre
Hot Tub Guy (uncredited)
Jonathan Goldstein
Motorbike Cop
John C. McGinley
Audrey Griswold
Leslie Mann
Clark Griswold
Chevy Chase
Ellen Griswold
Beverly D'Angelo
Chad
Charlie Day
Adena
Catherine Missal
Director of Photography
Barry Peterson
Producer
Chris Bender
Original Music Composer
Mark Mothersbaugh
Writer
Director
Songs
Executive Producer
Toby Emmerich
Richard Brener
Stunt Double
Ashley Rae Trisler
Steven Mnuchin
David Dobkin
Music Supervisor
Dave Jordan
Kelli Barksdale
Dave Neustadter
Script Supervisor
Lori Grabowski
Stunts
Corrina Roshea Bobb
Costume Designer
Debra McGuire
Characters
John Hughes
Production Assistant
Sean Patrick Burke
Production Design
Barry Robison
Casting
Lisa Beach
Editor
Jamie Gross
Sarah Katzman
Jeff Kleeman
Samuel J. Brown
Jojo Villanueva
Marc S. Fischer
Art Direction
Jeremy Woolsey
Makeup Department Head
Kimberly Jones
Construction Coordinator
Victor Anderson
Special Effects Coordinator
Dean Tyrrell
Art Department Coordinator
Stacie McKinnon
Hair Department Head
Shunika Terry
Set Costumer
Les Morgan
Makeup Artist
Mary Castor
Special Effects Supervisor
Russell Tyrrell
Key Hair Stylist
Lawrence Davis
Toni Cunningham
Sound Re-Recording Mixer
Gregg Landaker
Brad Sherman
Supervising Sound Editor
Tammy Fearing
Elmo Weber
Helicopter Camera
Michael Kelem
Dialogue Editor
Russell Farmarco
Sound Mixer
Mary H. Ellis
Property Master
Michael Sabo
Cameron Steenhagen
Ulrika Akander
Supervising ADR Editor
Chief Lighting Technician
James M. Cox